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Registro Completo |
Biblioteca(s): |
Biblioteca Rui Tendinha. |
Data corrente: |
29/12/2014 |
Data da última atualização: |
01/09/2015 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
BRASIL, G. A.; RONCHI, S. N.; NASCIMENTO, A. M.; LIMA, E. M. de.; ROMÃO, W.; COSTA, H. B. da.; SCHERER, R.; VENTURA, J. A.; LENZ, D.; BISSOLI, N. S.; ENDRINGER, D. C.; ANDRADE, T. U. de. |
Afiliação: |
Girlandia Alexandre Brasil; Silas Nascimento Ronchi; Andrews Marques do Nascimento; Ewelyne Miranda de Lima; Wanderson Romão; Helber Barcellos da Costa; Rodrigo Scherer; Jose Aires Ventura, Incaper; Dominik Lenz; Nazaré Souza Bissoli; Denise Coutinho Endringer; Tadeu Uggere de Andrade. |
Título: |
Antihypertensive Effect of Carica papaya Via a Reduction in ACE Activity and Improved Baroreflex. |
Ano de publicação: |
2014 |
Fonte/Imprenta: |
American Journal of Plant Sciences, 5, 2148-2153. 2014. |
Descrição Física: |
Planta Med. 2014 Nov ;80(17):1580-7. |
DOI: |
10.1055/s-0034-1383122 |
Idioma: |
Inglês |
Conteúdo: |
The aims of this study were to evaluate the antihypertensive effects of the standardised methanolic extract of Carica papaya, its angiotensin converting enzyme inhibitory effects in vivo, its effect on the baroreflex and serum angiotensin converting enzyme activity, and its chemical composition. The chemical composition of the methanolic extract of C. papaya was evaluated by liquid chromatography-mass/mass and mass/mass spectrometry. The angiotensin converting enzyme inhibitory effect was evaluated in vivo by Ang I administration. The antihypertensive assay was performed in spontaneously hypertensive rats and Wistar rats that were treated with enalapril (10 mg/kg), the methanolic extract of C. papaya (100 mg/kg; twice a day), or vehicle for 30 days. The baroreflex was evaluated through the use of sodium nitroprusside and phenylephrine. Angiotensin converting enzyme activity was measured by ELISA, and cardiac hypertrophy was evaluated by morphometric analysis. The methanolic extract of C. papaya was standardised in ferulic acid (203.41 ± 0.02 µg/g), caffeic acid (172.60 ± 0.02 µg/g), gallic acid (145.70 ± 0.02 µg/g), and quercetin (47.11 ± 0.03 µg/g). The flavonoids quercetin, rutin, nicotiflorin, clitorin, and manghaslin were identified in a fraction of the extract. The methanolic extract of C. papaya elicited angiotensin converting enzyme inhibitory activity. The antihypertensive effects elicited by the methanolic extract of C. papaya were similar to those of enalapril, and the baroreflex sensitivity was normalised in treated spontaneously hypertensive rats. Plasma angiotensin converting enzyme activity and cardiac hypertrophy were also reduced to levels comparable to the enalapril-treated group. These results may be associated with the chemical composition of the methanolic extract of C. papaya, and are the first step into the development of a new phytotherapic product which could be used in the treatment of hypertension. MenosThe aims of this study were to evaluate the antihypertensive effects of the standardised methanolic extract of Carica papaya, its angiotensin converting enzyme inhibitory effects in vivo, its effect on the baroreflex and serum angiotensin converting enzyme activity, and its chemical composition. The chemical composition of the methanolic extract of C. papaya was evaluated by liquid chromatography-mass/mass and mass/mass spectrometry. The angiotensin converting enzyme inhibitory effect was evaluated in vivo by Ang I administration. The antihypertensive assay was performed in spontaneously hypertensive rats and Wistar rats that were treated with enalapril (10 mg/kg), the methanolic extract of C. papaya (100 mg/kg; twice a day), or vehicle for 30 days. The baroreflex was evaluated through the use of sodium nitroprusside and phenylephrine. Angiotensin converting enzyme activity was measured by ELISA, and cardiac hypertrophy was evaluated by morphometric analysis. The methanolic extract of C. papaya was standardised in ferulic acid (203.41 ± 0.02 µg/g), caffeic acid (172.60 ± 0.02 µg/g), gallic acid (145.70 ± 0.02 µg/g), and quercetin (47.11 ± 0.03 µg/g). The flavonoids quercetin, rutin, nicotiflorin, clitorin, and manghaslin were identified in a fraction of the extract. The methanolic extract of C. papaya elicited angiotensin converting enzyme inhibitory activity. The antihypertensive effects eli... Mostrar Tudo |
Palavras-Chave: |
Carica papaya; Mamão; Rubi INCAPER 511. |
Thesaurus NAL: |
Antihypertensive; Hypertension. |
Categoria do assunto: |
Q Segurança Alimentar |
Marc: |
LEADER 03032naa a2200337 a 4500 001 1004730 005 2015-09-01 008 2014 bl uuuu u00u1 u #d 024 7 $a10.1055/s-0034-1383122$2DOI 100 1 $aBRASIL, G. A. 245 $aAntihypertensive Effect of Carica papaya Via a Reduction in ACE Activity and Improved Baroreflex.$h[electronic resource] 260 $c2014 300 $cPlanta Med. 2014 Nov ;80(17):1580-7. 520 $aThe aims of this study were to evaluate the antihypertensive effects of the standardised methanolic extract of Carica papaya, its angiotensin converting enzyme inhibitory effects in vivo, its effect on the baroreflex and serum angiotensin converting enzyme activity, and its chemical composition. The chemical composition of the methanolic extract of C. papaya was evaluated by liquid chromatography-mass/mass and mass/mass spectrometry. The angiotensin converting enzyme inhibitory effect was evaluated in vivo by Ang I administration. The antihypertensive assay was performed in spontaneously hypertensive rats and Wistar rats that were treated with enalapril (10 mg/kg), the methanolic extract of C. papaya (100 mg/kg; twice a day), or vehicle for 30 days. The baroreflex was evaluated through the use of sodium nitroprusside and phenylephrine. Angiotensin converting enzyme activity was measured by ELISA, and cardiac hypertrophy was evaluated by morphometric analysis. The methanolic extract of C. papaya was standardised in ferulic acid (203.41 ± 0.02 µg/g), caffeic acid (172.60 ± 0.02 µg/g), gallic acid (145.70 ± 0.02 µg/g), and quercetin (47.11 ± 0.03 µg/g). The flavonoids quercetin, rutin, nicotiflorin, clitorin, and manghaslin were identified in a fraction of the extract. The methanolic extract of C. papaya elicited angiotensin converting enzyme inhibitory activity. The antihypertensive effects elicited by the methanolic extract of C. papaya were similar to those of enalapril, and the baroreflex sensitivity was normalised in treated spontaneously hypertensive rats. Plasma angiotensin converting enzyme activity and cardiac hypertrophy were also reduced to levels comparable to the enalapril-treated group. These results may be associated with the chemical composition of the methanolic extract of C. papaya, and are the first step into the development of a new phytotherapic product which could be used in the treatment of hypertension. 650 $aAntihypertensive 650 $aHypertension 653 $aCarica papaya 653 $aMamão 653 $aRubi INCAPER 511 700 1 $aRONCHI, S. N. 700 1 $aNASCIMENTO, A. M. 700 1 $aLIMA, E. M. de. 700 1 $aROMÃO, W. 700 1 $aCOSTA, H. B. da. 700 1 $aSCHERER, R. 700 1 $aVENTURA, J. A. 700 1 $aLENZ, D. 700 1 $aBISSOLI, N. S. 700 1 $aENDRINGER, D. C. 700 1 $aANDRADE, T. U. de. 773 $tAmerican Journal of Plant Sciences, 5, 2148-2153. 2014.
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Biblioteca Rui Tendinha (BRT) |
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Registro Completo |
Biblioteca(s): |
Biblioteca Rui Tendinha. |
Data corrente: |
19/02/2018 |
Data da última atualização: |
19/02/2018 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
B - 1 |
Autoria: |
BAITELLO, D. C.; BARONI, D. F.; VIEIRA, K. M.; FREITAS, S. de J.; MENEGHELLI, C. M.; BERILLI, S. da S.; HADDADE, I. R.; VERDIN FILHO, A. C. |
Afiliação: |
Diego Corona Baitelle, UENF; Danilo Força Baroni, UENF; Kezia Moraes Vieira, UENF; Sílvio de Jesus Freitas, UENF; Caroline Merlo Meneghelli, UFES; Sávio da Silva Berilli, IFES Colatina; Ismail Ramalho Haddade, IFES Santa Teresa; Abraão Carlos Verdin Filho, Incaper. |
Título: |
Pit dimensions in the early development of Conilon coffee propagated by seeds and cuttings. |
Ano de publicação: |
2018 |
Fonte/Imprenta: |
Journal of Experimental Agriculture International, v. 20, Issue.: 1, p. 1-8, 2018. |
DOI: |
10.9734/JEAI/2018/39078 |
Idioma: |
Inglês |
Conteúdo: |
The knowledge about the interactions between pit dimensions and propagation methods can provide important information for the Conilon coffee crop since these basic steps can influence the entire production cycle of the tillage. The objective of this study was to access the initial development (vegetative and radicular) of Conilon coffee propagated by seed and stake and cultivated in pits with different dimensions. The experiment was a randomized block design with four replicates of three plants. The treatments were arranged in a 2x3 factorial scheme, with two propagation methods (seed and cutting), and three pit dimensions (20x20x20 cm, 30x30x30 cm and 40x40x40 cm). The number of leaves, stem diameter, plant height, main root length, root volume, dry mass of aerial part and root, and relation aerial/root part, were evaluated 18 months after transplanting. There was a significant interaction between the propagation methods and the pit dimensions, only for the number of leaves and root length, wherein the smaller pits, the seedlings propagated by seed were superior to the clonal ones. The other variables analyzed presented significant differences only for the pit dimensions factor. The initial development of the Conilon coffee isn't influenced by the propagation method. The pit dimensions directly affects the initial development of the Conilon coffee Incaper ?Vitória 8142' clone number 10, and pits with the largest dimensions provide an increase in the initial development of the plants. MenosThe knowledge about the interactions between pit dimensions and propagation methods can provide important information for the Conilon coffee crop since these basic steps can influence the entire production cycle of the tillage. The objective of this study was to access the initial development (vegetative and radicular) of Conilon coffee propagated by seed and stake and cultivated in pits with different dimensions. The experiment was a randomized block design with four replicates of three plants. The treatments were arranged in a 2x3 factorial scheme, with two propagation methods (seed and cutting), and three pit dimensions (20x20x20 cm, 30x30x30 cm and 40x40x40 cm). The number of leaves, stem diameter, plant height, main root length, root volume, dry mass of aerial part and root, and relation aerial/root part, were evaluated 18 months after transplanting. There was a significant interaction between the propagation methods and the pit dimensions, only for the number of leaves and root length, wherein the smaller pits, the seedlings propagated by seed were superior to the clonal ones. The other variables analyzed presented significant differences only for the pit dimensions factor. The initial development of the Conilon coffee isn't influenced by the propagation method. The pit dimensions directly affects the initial development of the Conilon coffee Incaper ?Vitória 8142' clone number 10, and pits with the largest dimensions provide an increase in the initial development of t... Mostrar Tudo |
Thesaurus NAL: |
Aerial part; Coffea canephora; Radicular system; Sexual and asexual propagation; Soil volume. |
Categoria do assunto: |
-- |
URL: |
https://biblioteca.incaper.es.gov.br/digital/bitstream/123456789/2992/1/BRT-pitdimensionsintheearlydevelopmentofconilon-verdinfilho.pdf
|
Marc: |
LEADER 02375naa a2200277 a 4500 001 1018644 005 2018-02-19 008 2018 bl uuuu u00u1 u #d 024 7 $a10.9734/JEAI/2018/39078$2DOI 100 1 $aBAITELLO, D. C. 245 $aPit dimensions in the early development of Conilon coffee propagated by seeds and cuttings.$h[electronic resource] 260 $c2018 520 $aThe knowledge about the interactions between pit dimensions and propagation methods can provide important information for the Conilon coffee crop since these basic steps can influence the entire production cycle of the tillage. The objective of this study was to access the initial development (vegetative and radicular) of Conilon coffee propagated by seed and stake and cultivated in pits with different dimensions. The experiment was a randomized block design with four replicates of three plants. The treatments were arranged in a 2x3 factorial scheme, with two propagation methods (seed and cutting), and three pit dimensions (20x20x20 cm, 30x30x30 cm and 40x40x40 cm). The number of leaves, stem diameter, plant height, main root length, root volume, dry mass of aerial part and root, and relation aerial/root part, were evaluated 18 months after transplanting. There was a significant interaction between the propagation methods and the pit dimensions, only for the number of leaves and root length, wherein the smaller pits, the seedlings propagated by seed were superior to the clonal ones. The other variables analyzed presented significant differences only for the pit dimensions factor. The initial development of the Conilon coffee isn't influenced by the propagation method. The pit dimensions directly affects the initial development of the Conilon coffee Incaper ?Vitória 8142' clone number 10, and pits with the largest dimensions provide an increase in the initial development of the plants. 650 $aAerial part 650 $aCoffea canephora 650 $aRadicular system 650 $aSexual and asexual propagation 650 $aSoil volume 700 1 $aBARONI, D. F. 700 1 $aVIEIRA, K. M. 700 1 $aFREITAS, S. de J. 700 1 $aMENEGHELLI, C. M. 700 1 $aBERILLI, S. da S. 700 1 $aHADDADE, I. R. 700 1 $aVERDIN FILHO, A. C. 773 $tJournal of Experimental Agriculture International$gv. 20, Issue.: 1, p. 1-8, 2018.
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